It helps that “retro games” now include early HD-era titles, such as Dead Space and Fallout 3. However, GOG.com has steadily grown its library of contemporary titles, from Baldur's Gate 3 to Carrion to the Destroy All Humans remake. Previously, you would be hard-pressed to find software that isn't at least five years old. You can download PC games directly from the GOG.com website, or you can use the optional GOG Galaxy desktop client. GOG.com is doing its part in the video game preservation movement. Many computer releases from that period became difficult to run in later versions of Windows, so GOG.com delivers many of them in DOSBox or ScummVM format, allowing the games to run on contemporary gaming PCs (as well as Linux and Mac machines). Old games represent the vast majority of GOG.com's selection, with hundreds of classic video games titles from the last two decades. We’re happy to report that GOG.com's service is pretty damn good, too, despite a few minor complaints. That two-pronged attack has enabled GOG.com to thrive in the Steam-dominated PC gaming marketplace. Although GOG.com specializes in retro titles, the company has a progressive outlook in regard to how it delivers content: None of its games feature restrictive digital rights management (DRM). GOG.com (the company formerly known as Good Old Games) is the store to visit if you have a hankering for Alone in the Dark, Baldur's Gate, Freddy Pharkas: Frontier Pharmacist, and other classic PC games from the 1990s and early 2000s.
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![]() Caffeine also increases the levels of neurotransmitters dopamine and norepinephrine. Caffeine stimulates the release of hormones adrenaline, cortisol, and epinephrine. Negative cognitive and emotional effects can also be a consequence of caffeine withdrawal. This can lead to frequent use and dependency, and therefore a worsening of withdrawal symptoms. Caffeine is quickly absorbed into the bloodstream and excreted through urine. ![]() While fatigue can be frustrating, allowing your brain’s neurotransmitters to stabilize should lead to more sustainable energy in the long run. Once caffeine is eliminated, many people feel tired and fatigued. Adenosine is a neurotransmitter that can cause fatigue in some circumstances. Caffeine improves energy and reduces drowsiness by blocking adenosine receptors. Tirednessįatigue is another symptom of caffeine withdrawal. Duration and severity of the withdrawal headaches vary. Once the brain has adapted, the withdrawal headaches will stop. Headaches are from the brain adjusting to the increase in blood flow. When you cease caffeine consumption, the constricted blood vessels expand.Īfter you stop using caffeine, blood flow to the brain increases. This constriction slows cerebral blood flow. Headaches happen because caffeine reduces your brain’s blood vessels. Headaches are often associated with caffeine withdrawal. Symptom duration varies but might end between 2 and 9 days.Ĭommon caffeine withdrawal symptoms include: The more caffeine consumed daily, the more intense withdrawal symptoms tend to be. Create your own customizable difficulty setting, eg cranking up the number of enemies but lowering damage taken for a more action-packed run.Customize which characters use new models. ![]()
Rochelle Neil ( Terminator: Dark Fate) as the fire-wielding Annie “Bonfire” Carby, one of Maladie’s motley gang. Pip Torrens ( The Crown) as Lord Gilbert Massen, a high-ranking government official leading the crusade against our heroines.īen Chaplin ( The Thin Red Line) as Inspector Frank Mundi, who’s torn between his police duties and moral compass.Įmmy-nominee Denis O’Hare ( American Horror Story) as Edmund Hague, a deranged doctor searching for the source of the powers.Īmy Manson ( Once Upon a Time) as the tortured, murderous Maladie, who derives power from pain. Tom Riley ( Da Vinci’s Demons) as Augustus “Augie” Bidlow, Lavinia’s sweet, awkward, younger brother with a secret of his own. James Norton ( Little Women) as Hugo Swann, the rich and irreverent proprietor of a den of iniquity. Olivia Williams ( The Ghost Writer) as Lavinia Bidlow, the wealthy benefactress funding the orphanage for Amalia’s outcasts, who are also known as the Touched. Rounding out this genre-bending drama’s acclaimed cast are: It falls to mysterious, quick-fisted widow Amalia True (Laura Donnelly) and brilliant young inventor Penance Adair (Ann Skelly) to protect and shelter these gifted “orphans.” To do so, they will have to face the brutal forces determined to annihilate their kind. ![]() But no matter their particular “turns,” all who belong to this new underclass are in grave danger. Victorian London is rocked to its foundations by a supernatural event which gives certain people – mostly women – abnormal abilities, from the wondrous to the disturbing. RELATED: Joss Whedon Departs HBO Series The NeversĪugust, 1896. ![]() Check out the new The Nevers Season 1 Part 1 trailer in the player below! ![]() The series will air on HBO and be available to stream on HBO Max. Part Two’s six episodes will follow at a later date, to be announced. HBO has revealed that their new drama series The Nevers debuts Part One of its first season with six episodes beginning on Sunday, April 11 (9:00-10:00 p.m. (There are 3 such APIs in my experience, only the highest-level API, MCI, is affected). Pidgeot: That *particular* issue is because the MIDI synthesizer that Windows uses has a crazy long startup time when using the high-level MIDI API in modern Windows versions. It is theoretically possible to hack the executable to replace the existing code - the source code helps to understand the structure of the code, so it is easier to reverse engineer things - but that is still going to require a fair amount of effort :) It also seems like part of the music code might be in one of those missing libraries, but I haven't checked if it actually makes use of it. This, however, requires modifying the source code, and unfortunately, the source code included here is not complete it refers to some libraries which are not included, so it is not really possible to make a custom build. the stream-based API, which does not exhibit this issue. The other, more reliable option, is to switch MIDI APIs, to e.g. One option is therefore to tell Windows to use a different MIDI synth by default - but googling suggests this has been removed in Windows 8, and even so, it would have to be up to each user to do so. That *particular* issue is because the MIDI synthesizer that Windows uses has a crazy long startup time when using the high-level MIDI API in modern Windows versions. Follow his guide on Steam/Discord/Github.Zeffyr: Small lags (2-3 secs) happened to me few times, between MIDI tracks - one ended, the second one was about to start and game froze. I would like to draw your attention to WizzardMaker | Jonas.He almost single-handedly provides a completely fixed version of Airline Tycoon. Right klick the AT-Logo in steam and go to Manage -> Browse Local Data -> Check files for errors (or something similar) ![]() open the aqrit.cfg file with the Editor and change ColorFix from 1 to 0ħ. compatibility of the AT.ext on Windows XP/Service Pack 3Ĥ. aqrit.cfg file (downloaded and placed in the AT folder)Ģ. Here a short checklist for troubleshooting:ġ. Please let us know if that is helps you out. Seems a fansite did find a fix that is unoffical, but will list it here just in case it will help some of you.ĭownload the file "adtfix.rar" from in the installation folder and it should fix the issues. Here the original contribution of the game dev: If it still does not work change the value ColorFix in the aqrit.cfg file (open the file with the Editor) from 1 to 0 and try again. ![]() Set the compatibility of the AT.exe (in the same folder) to Windows XP/Service Pack 3. ![]() I've been digging through some forums and found a solution.įirst of all big thanks to Zyddie (Game dev) and Mattanst (reupload of the file).ĭownload the file at the following reddit page and move all files inside to the installation folder of Airline Tycoon (Airline Tycoon Icon -> Manage -> Browse Local Data) There are more and more reports about problems with the graphics of ATD on newer systems. There is also the possibility that the student simply got bored, distracted, or otherwise failed to complete his or her “homework” and left an unfinished text! Whether they took the unfinished text with them, or left it in the care of their teacher, the text could be lost and remain incomplete. For example, students typically interrupted their classes during the rainy season, when they returned to their villages to cultivate the fields. Therefore, if they do not complete their study of this text, again their copy becomes a fragment of the whole. Students can only copy the parts of a text they have learnt from their teacher. Also, if this person making the copy failed to return the portion of the original text, the result would be two fragments: the borrowed section and the large compendium missing its section (both of which might now find themselves in different manuscript collections!).Ī key feature of the system of Islamic learning that is common across West Africa is the copying of texts. This copy, if it survived, would therefore appear to be a fragment, since it is only a portion of the whole compendium. If, for example, somebody wanted to understand the rules around zakat (alms-giving), they might borrow and copy the relevant section from a compendium such as the Risālah of Ibn Abī Zayd. This was most often the case for large legal treatises. One advantage of the looseleaf format was that owners could lend portions of the text to fellow scholars to copy or memorize. However, during earlier periods where these manuscripts were in constant use for learning and teaching, the possibilities for losing pages were also many. While cherishing these items as a family heirloom, again the pages could have been disordered or lost during storage or movement, if the new owners did not understand the catchword system. What is more, in more modern times such manuscripts were inherited by children or relatives who did not necessarily speak Arabic or understand the content of these documents. This system made it far more likely for pages to become disordered or to be lost during movement.Īnd-with most of the manuscript owners being nomadic, or at least changing their residence with the seasons-the possibilities for loss are increased. Page order was recorded not with page numbers but with catchwords: the first word of the new leaf would be recorded at the corner of the previous one. Manuscripts from this part of the world are typically unbound, with the loose leaves held together in a leather covering that is tied. One reason has to do with the fundamental form of a West African manuscript. There are many reasons why we encounter so many fragments across the Timbuktu collections. Of the 7,751 manuscripts we have cataloged so far in the Mamma Haidara Library, 28 percent are fragments however, as fragments are typically more challenging to identify and catalog, the number is likely to rise as we tackle more of this large collection. ![]() The figure for the Bibliothèque de Manuscrits al-Imam Essayouti (2,696 manuscripts) is 43 percent. In total, 38 percent of the 7,537 items in the Aboubacar ben Said Library are fragments. At the beginning of the 21st century, the approach to scholarship and utilization of manuscripts changed radically, as digitization, creation of online databases, interconnected portals and links to universal portals, catalogs of manuscripts and published materials, among other innovations, redefined the ways knowledge of Islamic history is generated, accessed, and utilized.A large amount of the manuscripts digitized in Timbuktu, Mali, that we at HMML have cataloged are fragments-missing pages at the beginning, the end, or the middle of the text, or sometimes all of the above. ![]() The manuscript tradition in Islam is as old as the faith itself it was one of the earliest material sources on Islamic sciences, and in the case of Africa, it provided a treasure trove of materials. Although Judeo-Christian, Late-Antique, and pre-Islamic materials provided the earliest historical sources on Islam and its people, the Qur’an, hadith (statements of the Prophet Muhammad), and the sira/maghāzī (biography/expeditions) were the first original sources on Islamic history on which later writings, including those from Africa, drew. ![]() Africa came in contact with Islam right from the birth of the faith in the 7th century. Of central interest here are the historical sources on Islam and Africa, the role and contributions of manuscripts to the narrative, and how the new cyber world has become a domain for those sources as instruments for the generation and utilization of knowledge. At one point, a male character tells Fanny (Bronwyn James), “Women will always be at the mercy of men’s power,” and she offers her own insight: “It’s not your power that we’re at the mercy of. This season doubles down on all of this, including exploring the hypocrisy of men and how they maintain the current power structure to keep women dependent. ![]() Margaret also still appears to have a conscience and regrets that raising her two daughters Charlotte and Lucy (Eloise Smyth) into the life, which includes auctioning off their virginity, wasn’t the only way she could succeed in life. Of course, the big difference is that Golden Square perpetuates rape – providing unwilling virgins to sadistic men – while Greek Street provides consenting women who want the protection of a house, instead of just freelancing in the back alleys. Quigley is the Georgian counterpart of this, and thus, even though she continues to put women – young girls, in fact – in horrifying positions, she’s only a few shades of grey morality-wise from Margaret. Jessica Brown Findlay and Samantha Morton, “Harlots” One of the many results of the current #MeToo movement is the revelation of just how much women, driven by trying to advance or survive in a patriarchal world, have helped to perpetuate the abuse and oppression of fellow women. ![]() Nevertheless, in this way, it is realistic. This feels like the classic “crabs in a barrel” concept in which one crab will keep another crab from escaping by dragging it down, thus dooming everyone. One of the problematic narrative issues with “Harlots” is its focus on women tearing down other women, which seems counterproductive when they’re all dealing with lives that are already hard enough as it is. This seeming betrayal, however, is part of her revenge scheme to take down Quigley, who is responsible for having forced her mother into whoring as a child, which in turn forced her subsequent children into the life. The series picks up with in-demand harlot Charlotte Wells (Jessica Brown Findlay) having abandoned her mother Margaret’s (Samantha Morton) brothel on Greek Street for Golden Square, the high-end house of rival bawd Lydia Quigley (Lesley Manville). ![]() “The Handmaid’s Tale” may have just ended its latest season, but the commentary on female oppression continues on Hulu with the return of “Harlots.” Now in its sophomore season, the drama about warring brothels digs deeper into the underlying issues that have created the enmity, along with the gender inequality that has forced the women into such cutthroat circumstances in 18th-century Georgian London. ![]() ![]() Adenosine also stops triggered ventricular arrhythmias and many focal atrial tachycardias. Adenosine stops atrioventricular nodal arrhythmias, e.g., atrioventricular reentrant tachycardia and atrioventricular nodal reentrant tachycardia. However, adenosine is more stable at room temperature than adenosine triphosphate. Continuous electrocardiogram recordings during adenosine administration can aid clinicians in differentiating between true adenosine resistance (non- atrioventricular node) and transient adenosine effect (short half-life).Īdenosine triphosphate is metabolized into adenosine when given intravenously was used to treat arrhythmias, and it has similar clinical efficacy to intravenous adenosine. Adenosine failure can occur for two main reasons in treating supraventricular tachycardia: 1) It has a very short half-life, and 2) A non- atrioventricular node-dependent supraventricular tachycardia. Adenosine primarily affects the atrioventricular node to stop the arrhythmia. Pediatric supraventricular tachycardia is often dependent on the atrioventricular node for its propagation. The 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care (pediatric life support) gives adenosine a class I recommendation for hemodynamically stable supraventricular tachycardia. The clinicians concluded that higher doses of adenosine might be necessary for refractory supraventricular tachycardia. The infant returned to sinus rhythm with a higher dose of adenosine. The clinicians tried electrical cardioversion, but the supraventricular tachycardia was resistant. An infant presented with unstable supraventricular tachycardia. If not promptly treated, it can cause cardiogenic shock and heart failure. Pediatric supraventricular tachycardia is a common arrhythmia with great clinical significance. Second-line treatments include beta-blockers and calcium channel blockers. The European Society of Cardiology guidelines advocates using vagal maneuvers and adenosine as first-line therapies in diagnosing and treating supraventricular tachycardia. However, trabodenoson was not found to be effective in a phase III clinical trial. The experimental adenosine A1 receptor agonist, trabodenoson, is proposed to increase aqueous humor outflow by stimulating trabecular meshwork cells’ production of matrix metalloproteinases which clears accumulated debris from the eye. Endogenous adenosine appears to play a role in the pathophysiology of glaucoma. Worldwide, glaucoma is the second leading cause of blindness. Therapeutically, adenosine is used for its antiarrhythmic properties in supraventricular tachycardia (SVT) and can function as a diagnostic tool, depending on the type of SVT. Diagnostically, adenosine is one pharmaceutical agent used in a myocardial perfusion stress imaging study for its vasodilatory effects. 5 foods to avoid if you have IBS.Adenosine can serve as a diagnostic or therapeutic agent. Spilling the beans: How much caffeine is too much?. Sports drinks and energy drinks for children and adolescents: Are they appropriate?. Schneider MB, Benjamin HJ, Committee on Nutrition and the Council on Sports Medicine and Fitness. The American College of Obstetrics and Gynecologists. How much coffee can I drink while I'm pregnant?. The safety of ingested caffeine: A comprehensive review. Temple JL, Bernard C, Lipshultz SE, Czachor JD, Westphal JA, Mestre MA. Caffeine content labeling: A missed opportunity for promoting personal and public health. ![]() Placebo caffeine reduces withdrawal in abstinent coffee drinkers. A brief manualized treatment for problematic caffeine use: A randomized control trial. Faster but not smarter: Effects of caffeine and caffeine withdrawal on alertness and performance. Rogers PJ, Heatherley SV, Mullings EL, Smith JE. Caffeine and primary (migraine) headaches-friend or foe?. ![]() The common plant that could kill your dog: Vet issues urgent warning to owners to be vigilant.Witness describes horrific scenes after finding murdered British doctor who was shot dead in front of his family after taking a wrong turn in South Africa. ![]() Neighbours reveal shock as girl, 10, is found dead at £550,000 Surrey house 'just five months after her family moved in': Murder probe is launched into death with officers seen removing bags of evidence.Horoscope today: Daily guide to what the stars have in store for YOU - August 11, 2023.Furious Brits slam 'embarrassing' Americans for naming their children after UK cities - after one mother's VERY 'cringe' moniker choice sent the internet into a frenzy.Tory MP Theresa Villiers failed to declare that she held £70,000 of shares in energy giant Shell while she was environment secretary.Nicola Sturgeon says she wants the police probe into the SNP finances 'to be over' as the former First Minister says the investigation and her subsequent arrest has been 'difficult' and 'traumatic'.Owners of Britain's 'wonkiest pub' that burned down in 'arson attack' are now accused of tearing down 20ft-tall trees, ripping up orchids and destroying wildlife in 'mini personal New Forest' after gutting ANOTHER popular village boozer.putting a spring in his step after court heard the Olympic diver's husband twisted a BBC presenter's arm who then punched him in a Soho nightclub EDEN CONFIDENTIAL: Tom Daley is set to receive a £4million business payout.Controlling boyfriend who flushed his partner's rabbit down the toilet is on the run: Fugitive thug, 23, is jailed in his absence after campaign of abuse.William is given command of Harry's old Army unit: King grants Prince of Wales prestigious RAF position while roles Andrew lost after Virginia Roberts scandal go to Kate and Sophie in major royal reshuffle.Shocking moment British man, 57, is seen on CCTV being 'led to his gruesome death - after being lured to meet girl, 19, as part of lethal injection honey-trap murder plot that saw him pumped full of poisonous chemicals' in a flat in Turkey.It is an excellent idea that is already proving to be very attractive in a very particular market niche. For a price of approximately US $1.5 million, superyacht owners will have access to unparalleled immersive experiences and explore places where no human has gone before without need for professional training and the assurance that in the case of emergency, the submarine will naturally float back to the surface. The new DeepFlight Dragon aims to revolutionize the market offering user-friendly, comfortable, and efficient private submarines. Additionally, the model is equipped with exterior fixings to incorporate peripheral accessories such as high-definition cameras, high reach lights or ultrasound microphones to detect the sounds emitted by whales for easy location of these enormous marine mammals. Its exterior and interior design have been carefully developed to be quickly inserted into the superyacht market, a niche in which the company already has celebrity clients such as Richard Branson, Tom Perkins, and Dietrich Mateschitz, among others. While underwater, it can reach a cruising speed of four knots (7.4 km / h) and allows you to dive up to 400 feet (122 m) deep. With a range of up to six hours-provided by lithium battery electric propulsion-this craft, weighing 4,000 pounds 16 feet 5 inches long, 6 feet 3 inches wide and just 3 feet 7 inches tall is very easy to store in the garages of large vessels. The latter allows the Dragon to be the only personal submarine with the ability to rise and dive vertically, facilitating and improving the maneuver of immersive experiences. With an exterior design similar to that of a Formula 1 car, the Dragon controls its position and depth with six propellers, two of which are located in the stern and the other four fit horizontally on both sides of the bow and the stern. It is also the first personal submarine with capacity for autonomous underwater buoyancy, which means that in any event, its own structural composition will ensure that the vessel will naturally float back to the surface, making it very safe.The company developed a monitoring and control immersion system called Deep Flight Drive Manager (DDM), which manages critical aspects of the dive such as depth controls, battery consumption, oxygen consumption and altitude controls, which ultimately prevent the need for a third professional pilot. His most significant achievement is the Dragon, a small submarine, that can be driven by almost anyone any occupant using a series of intuitive controls patented by the brand. ![]() While entrepreneurs are typically sales driven, he says it’s vital that they also look at costs. “At the end of the day, it may be a mix of all of these elements.”įontaine says doing these calculations can help companies decide how to make the most appropriate changes. However, that’s easier said than done-the competitive landscape will not allow you to have that flexibility on selling price,” he says, adding that you would have more control to reduce cost of sales, to a certain limit. If you can increase your price with the same volume, that will increase your revenue and your gross margin. A third option might be to find flexibility in your selling price. “You can also aim for higher volumes, through increasing your market penetration or gaining new customers. “One way is simply to reduce your indirect costs,” says Fontaine. There are various ways to lower your break-even point. Components that impact profitability and, as a result, break-even point: In short, a sensitivity analysis can improve the resiliency of your business. Need to know the effect of a 10% drop in your sales? Or the impact of a 5% increase in the cost of your materials? A sensitivity analysis will provide answers and allow you to prepare a strategy to deal with these eventualities. To understand the effect that different variables’ fluctuations have on your business’s profitability, you’ll need to use a financial model called a sensitivity analysis. “But remember there are only a few components that can be adjusted-indirect costs, and gross margin percentage, through either volume of sales in units, unit selling price or cost per unit.” Perform a sensitivity analysis It’s important to make adjustments, if needed,” says Fontaine. The same exercise could also be done using a range of gross margin percentages.” You’ll then see a range of break-even points. “Try calculating break-even using examples of $200,000, $250,000 and $350,000 in total indirect costs. When calculating your initial break-even point, you’ll need to establish a range of scenarios.” “For example, if total indirect costs are now trending more towards $350,000 instead of $250,000, your break-even point will now be higher, at $1.4 million. Unfortunately, the reality is that after a month or two, or a quarter or two, you may have to re-visit that break-even point,” explains Fontaine. In a perfect world, you would meet all components of your budget. “Let’s say that with estimated total indirect costs of $250,000 and a gross margin percentage of 25%, you calculate that you’ll need to achieve $1 million in revenue to break even. It can be easy to convince yourself to increase indirect costs to drive business growth, but if you do so in advance of the additional business, you will need to clearly understand the impact that these additional costs will have on the new volume.” The break-even rangeįontaine says that since every business experiences fluctuations in revenue, the break-even point should be thought of as a range, rather than a specific number. “Sometimes, the most difficult part for entrepreneurs is to realize the full impact of indirect costs on overall profitability. ![]() When to use a break-even analysisĪ break-even analysis is essential for understanding how your business is doing and how to press on, according to Fontaine. A break-even analysis reveals how the break-even point changes for adjustments such as the unit’s selling price. The break-even point, on the other hand, establishes a threshold for success and helps set clear sales targets. “So, the formula is the same: indirect costs divided by your gross margin percentage.” The difference between break-even point and break-even analysisĪ break-even analysis looks at where your business is headed and what course of action might be taken to reduce your break-even point and increase profit. A consulting business would be a good example of that,” Fontaine explains. The only difference would be in the type of volume it sells, for example, number of hours instead of number of units or products. “The service industry also has indirect costs and gross margin values. Growth & Transition Capital financing solutionsĬalculating the break-even point for a service businessĭespite their trade not being in units, companies that provide a service can still calculate their break-even point. Kauffman Fellows Program Partial Scholarship Venture Capital Catalyst Initiative (VCCI) ![]() Industrial, Clean and Energy Technology (ICE) Venture Fund |
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